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Cardiology: Clinical Research Program

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Cardiology: Clinical Studies Open For Enrollment

 

PROTOCOL CY 6031 A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF CK3773274 IN ADULTS WITH SYMPTOMATIC HYPERTROPHIC CARDIOMYOPATHY AND LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION

Eligibility

  • Symptomatic Hypertrophic cardiomyopathy
  • Hemoglobin at least 10 g/dL at screening
  • No moderate-severe valvular aortic stenosis and/or regurgitation

Enrollment Status: Enrolling

Study Information

ClinicalTrials.gov | NCT05186818

Principal Investigator

Dr. Srihari Naidu

Contact for Study Screening

Erida.Castro@wmchealth.org and FNU.Namrata@wmchealth.org

 

PROTOCOL CY 6022 AN OPEN-LABEL STUDY OF CK3773274 FOR PATIENTS WITH SYMPTOMATIC HYPERTROPHIC CARDIOMYOPATHY (HCM)

Eligibility

  • Symptomatic Hypertrophic cardiomyopathy
  • Any acute or serious comorbid

Enrollment Status: Enrolling

Study Information

ClinicalTrials.gov | NCT04848506

Principal Investigator

Dr. Srihari Naidu

Contact for Study Screening

Erida.Castro@wmchealth.org and FNU.Namrata@wmchealth.org

 

Observational Study Protocol CV027-012 DELIVER INSIGHTS IN HYPERTROPHIC CARDIOMYOPATHY AND OBSERVATIONAL OUTCOMES IN REAL WORLD (DISCOVER-HCM): UNITED STATES PROSPECTIVE REGISTRY STUDY

Eligibility

  • Diagnosis of obstructive Hypertrophic cardiomyopathy

Enrollment Status: Enrolling

Study Information

ClinicalTrials.gov | NCT05489705

Principal Investigator

Dr. Srihari Naidu

Contact for Study Screening

Erida.Castro@wmchealth.org and FNU.Namrata@wmchealth.org

 

A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein (a)

Eligibility

  • Atherosclerotic Cardiovascular Disease by the history of either Myocardial infarction or Coronary revascularization.
  • No severe renal dysfunction.

Enrollment Status: Enrolling

Study Information

ClinicalTrials.gov | NCT05581303

Principal Investigator

Dr. Diwakar Jain

Contact for Study Screening

Erida.Castro@wmchealth.org and FNU.Namrata@wmchealth.org