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Hematology: Clinical Research Program

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Hematology: Clinical Studies Open For Enrollment

 

Allogeneic Stem Cell Transplant to Induce Mixed Donor Chimerism in Patients with Sickle Cell Disease & Thalassemia NYMC 556

Eligibility

  • Subject is 30 years of age or younger
  • Diagnosis of Homozygous Hemoglobin S Disease or Heterozygous Hemoglobin Sickle Cell (SC) or S 0/+ thalassemia, or Sickle/variant resulting in Chronic Hemolytic Anemia with hemoglobin (HgB) less than or equal to 10 mg/dL

Enrollment Status: Enrolling

Study Information

ClinicalTrials.gov | NCT00408447

Principal Investigator

Mitchell S. Cairo, MD

Contact for Study Screening

Lauren_Harrison@nymc.edu

 

Analysis of Patients Treated for Chronic Granulomatous Disease

Enrollment Status: Enrolling

Principal Investigator

Jordan Brittni Milner, MD

Contact for Study Screening

Lauren_Harrison@nymc.edu

 

A prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID Disorders

Enrollment Status: Enrolling

Principal Investigator

Jordan Brittni Milner, MD

Contact for Study Screening

Lauren_Harrison@nymc.edu

 

The use of dose dense rituximab for high risk patients with newly diagnosed acute immune thrombocytopenic purpura

Enrollment Status: Enrolling

Principal Investigator

Jordan Brittni Milner, MD

Contact for Study Screening

Lauren_Harrison@nymc.edu

 

A Pilot Study to Determine the Safety of Defibrotide in Children with High Risk Kawasaki Disease (NYMC-204)

Eligibility

  • Subject is 11 years of age or younger
  • Kawasaki disease presumptive diagnosis and initiation of defibrotide within 96 hours from the conclusion of IVIG treatment 

Enrollment Status: Enrolling

Study Information

ClinicalTrials.gov | NCT04777422

Principal Investigator

Mitchell S. Cairo, MD

Contact for Study Screening

Lauren_Harrison@nymc.edu

 

NYMC-598, A Phase II Trial of Targeted Immunotherapy with Daratumumab Following Myeloablative Total Body Irradiation (TBI)-Based Conditioning and Allogeneic Hematopoietic Cell Transplantation in Children, Adolescents and Young Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia and Lymphoma (T ALL/T LLy) (ALLO-T-DART) (NCT04972942)

Eligibility

  • Age: less than or equal to 39 years
  • Diagnosis: T-cell acute lymphoblastic leukemia in second or subsequent remission (less than or equal to 5% blasts).
    • Relapsed T-cell lymphoblastic lymphoma with complete response after reduction therapy.
  • Donor Status: Planned allogeneic stem cell transplantation with donor identified.

Enrollment Status: Enrolling

Study Information

ClinicalTrials.gov | NCT04972942

Principal Investigator

Mitchell S. Cairo, MD

Contact for Study Screening

Lauren_Harrison@nymc.edu